[Ref], Common (1% to 10%): Skin rash, pruritus, alopecia, Uncommon (0.1% to 1%): Pigmentary changes, pigmentation disorders in skin and mucous membranes, bleaching of hair, Rare (0.01% to 0.1%): Attacks of psoriasis, Very rare (less than 0.01%): Dermatitis bullous eruptions, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis, drug rash with eosinophilia and systemic symptoms (DRESS) syndrome, photosensitivity, exfoliative dermatitis, acute generalized exanthematous pustulosis (AGEP), Frequency not reported: Urticaria, angioedema, Postmarketing reports: Hair color changes[Ref], Rare (0.01% to 0.1%): Exacerbation/precipitation of porphyria, Postmarketing reports: Hypoglycemia, decreased appetite, porphyria[Ref], Uncommon (0.1% to 1%): Dizziness, nerve deafness, vertigo, tinnitus, Rare (0.01% to 0.1%): Seizure/convulsions, neuromyopathy, Very rare (less than 0.01%): Nystagmus, ataxia, Postmarketing reports: Extrapyramidal disorders (e.g., dystonia, dyskinesia, tremor), deafness[Ref], Common (1% to 10%): Affect/emotional lability, Very rare (less than 0.01%): Psychosis, suicidal behavior, nightmares, Uncommon (0.1% to 1%): Abnormal liver function tests, Very rare (less than 0.01%): Fulminant hepatitis, Postmarketing reports: Acute/fulminant hepatic failure[Ref], Uncommon (0.1% to 1%): Sensorimotor disorders, Frequency not reported: Absent/hypoactive deep tendon reflexes, Postmarketing reports: Skeletal muscle myopathy/muscle weakness/neuromyopathy (leading to progressive weakness, atrophy of proximal muscle groups), depression of tendon reflexes, abnormal nerve conduction studies[Ref], Myopathy has been reversible after therapy discontinuation, but recovery has taken many months. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Other side effects not listed may also occur in some patients. Why not just give it to everyone and monitor their outcomes? Abnormal Function Of The Cornea In The Eye. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. Background. Along with its needed effects, hydroxychloroquine may cause some unwanted effects. Side Effects of Hydroxychloroquine. Common side effects of hydroxychloroquine include irritability, headache, weakness, hair lightening or loss, stomach upset, nausea, dizziness, muscle pain, rash, and itching. Skin conditions like psoriasis or porphyria and bleaching of hair and also suffer from mild hair loss—tinnitus, which is ringing in the ear. O 0. It can kill children. Side effects aren't common. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known. AGEP has been associated with fever and hyperleukocytosis. By the mid-1950s, doctors were using hydroxychloroquine to treat the autoimmune disorders lupus and rheumatoid arthritis. There are potential cardiovascular side effects associated with its use. Available for Android and iOS devices. Cerner Multum, Inc. "Australian Product Information." Some of the side effects include: The more common side effects of hydroxychloroquine include: Headache; Dizziness; Diarrhea; Stomach Cramps; Vomiting; Apart from these, there are some serious side effects of hydroxychloroquine too. Maculopathies and macular degeneration have been reported (onset ranging from 3 months to several years of exposure to this drug) and may be irreversible. hair loss. The side effect of hydroxychloroquine is numerous, which include: Damage of the eye is caused by visual problems that can be permanent, especially when taken an overdose. Hydroxychloroquine is generally considered safe for treatment of malaria and autoimmune diseases, and an estimated 90 percent of people won’t experience any side effects if they take the drug. However, in some people hydroxychloroquine can cause: skin rashes, especially those made worse by sunlight; feeling sick (nausea) or indigestion; diarrhoea; headaches; bleaching of the hair or mild hair loss; tinnitus (ringing in the ears) visual problems. This content does not have an English version. Another reason why experts are cautious about using hydroxychloroquine to treat COVID-19 is because of its numerous side effects. In fact, a small recent study showed that up to 11 percent of coronavirus patients on hydroxychloroquine and azithromycin are in the so-called "red zone" for potential cardiac side effects. Some Side Effects of Hydroxychloroquine. All rights reserved. If experienced, these tend to have a Severe expression. We have summarised output from ESC meetings and journals related to this below. Side Effects of Hydroxychloroquine. Prasco Laboratories, Cincinnati, OH. Sanofi Winthrop Pharmaceuticals, New York, NY. Common side effects may include vomiting, headache, changes in vision, and muscle weakness. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Applies to hydroxychloroquine: compounding powder, oral tablet, QT interval prolongation has been reported in patients with specific risk factors, which may lead to arrhythmia (torsade de pointes, ventricular tachycardia). The side effect of hydroxychloroquine is numerous, which include: Damage of the eye is caused by visual problems that can be permanent, especially when taken an overdose. In general, skin rash, pruritus, pigmentation disorders in skin and mucous membranes, bleaching of hair, and alopecia resolved readily when therapy was discontinued. Our Plaquenil (hydroxychloroquine) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. Here, we provide a systematic review of the psychiatric side effects associated with chloroquine and hydroxychloroquine. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. I would like to subscribe to Science X Newsletter. Their mechanism of action is not entirely understood. Although not all of these side effects may occur, if they do occur they may need medical attention. Along with its needed effects, a medicine may cause some unwanted effects. Side effects of hydroxychloroquine and its implications for COVID-19 patients It is widely known that President Trump views hydroxychloroquine as the magic cure for the deadly COVID-19 contagion. Chloroquine and cardiovascular side effects There has been increased interest in the use of chloroquine and hydroxychloroquine in the context of COVID-19 which is currently under evaluation in trials. All rights reserved. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Blurred vision (temporary) and extraocular muscle palsies (reversible) were due to disturbance of accommodation, which was dose dependent and reversible. Plaquenil (R). The drug was readily available. The malaria drug hydroxychloroquine, which has been promoted as a potential treatment for COVID-19, is known to have potentially serious effects on heart rhythms. "Product Information. Mayo Clinic does not endorse companies or products. 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